Aflatoxin

The aim of this study was to enumerate the serum aflatoxin B1 (AFB1) in children 6-59 months of age, and estimate its association with linear growth in these children. To accomplish this aim, the team conducted a cross-sectional study that focused on understanding the extent and level of aflatoxin exposure as measured through presence in a serum sample from children. We also studied the association between serum aflatoxin and chronic malnutrition (stunting), accounting for other risk factors. The specific objectives of this study include: 1.

O objectivo principal deste estudo foi avaliar os níveis de aflatoxina B1 (AFB1) sérica em crianças de 6 a 59 meses de idade e estimar a sua associação com o crescimento linear nessas crianças. Para atingir esse objectivo, a equipa conduziu um estudo transversal que se focou em compreender a extensão e o nível de exposição à aflatoxina, determinando a sua presença em amostras de soro de crianças. Também se estudou a associação entre aflatoxina sérica e desnutrição crónica, considerando outros fatores de risco. Os objectivos específicos deste estudo incluem: 1.

Abstract

Aflatoxin M1 (AFM1) is the hydroxylated metabolite of aflatoxin B1 (AFB1) formed in the liver of mammals and subsequently excreted in breastmilk (BM) of mammals. Humans are exposed to AFM1 mainly through the consumption of aflatoxin contaminated milk and foods. Determining levels of AFM1 is of significant public health importance due to the risk of exposure to breastfeeding infants. The objective of this study is to determine the prevalence of AFM1 in BM and assess factors associated with BM AFM1 levels in mothers.

Abstract

Background

Naturally occurring aflatoxins may contribute to poor growth and nutritional statuses in children.

Objectives

We analyzed the relationship between contemporary and lagged aflatoxin exposure and 1) length-for-age z-score (LAZ); and 2) length, knee-heel length, stunting, weight-for-age z-score (WAZ), and weight-for-length z-score (WLZ).

Methods

Abstract

Objectives

To examine the association between aflatoxin (AF) exposure during pregnancy and rate of gestational weight gain (GWG) in a sample of pregnant women of mixed HIV status in Gulu, northern Uganda.