Paudel, Krishna

Prevalence and associated factors of breastmilk aflatoxin M1 levels in mothers from Banke, Nepal

Publication Type

Abstract

Aflatoxin M1 (AFM1) is the hydroxylated metabolite of aflatoxin B1 (AFB1) formed in the liver of mammals and subsequently excreted in breastmilk (BM) of mammals. Humans are exposed to AFM1 mainly through the consumption of aflatoxin contaminated milk and foods. Determining levels of AFM1 is of significant public health importance due to the risk of exposure to breastfeeding infants. The objective of this study is to determine the prevalence of AFM1 in BM and assess factors associated with BM AFM1 levels in mothers.

Aflatoxin exposure and child nutrition: measuring anthropometric and long-bone growth over time in Nepal

Publication Type

Abstract

Background

Naturally occurring aflatoxins may contribute to poor growth and nutritional statuses in children.

Objectives

We analyzed the relationship between contemporary and lagged aflatoxin exposure and 1) length-for-age z-score (LAZ); and 2) length, knee-heel length, stunting, weight-for-age z-score (WAZ), and weight-for-length z-score (WLZ).

Methods

Relatively Low Maternal Aflatoxin Exposure Is Associated with Small-for-Gestational-Age but Not with Other Birth Outcomes in a Prospective Birth Cohort Study of Nepalese Infants

Publication Type

This study used maternal and newborn data from the AflaCohort Study, an ongoing birth cohort study in Banke, Nepal (= 1621). Data on aflatoxin B1(AFB1)-lysine adducts in maternal serum were collected once during pregnancy (at mean ± SD: 136 ± 43 d of gestation). Maternal serum AFB1-lysine adduct concentration was measured via HPLC.

Factors associated with anemia in pregnant women in Banke, Nepal

Publication Type

Anemia through pregnancy is highly correlated with poor birth outcomes, especially low birth weight (LBW). The Nepal DHS 2011 reports prevalence of anemia in pregnant women at 48%.

Factors associated with mid upper arm circumference in pregnant women in Banke, Nepal

Publication Type

Rates of weight gain in pregnancy are associated with infant weight for age, length for age and weight for length and are predictive of postnatal growth at 6 months of age. The study examines factors linked with low mid upper arm circumference (MUAC) in pregnant women in Banke Nepal.